Harnessing nc886 to overcome immune and apoptotic barriers in adenoviral gene therapy

Related Experiment Video

Updated: May 20, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.3K

Mohamed Hammad1, Hossam M Ashour2

  • 1Developmental and Stem Cell Biology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

Molecular Therapy. Nucleic Acids
|March 24, 2025
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
13:36

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches

Published on: May 6, 2015

10.3K
Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
15:33

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

15.8K

Related Experiment Videos

Last Updated: May 20, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.3K
Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
13:36

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches

Published on: May 6, 2015

10.3K
Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
15:33

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

15.8K

Related Concept Videos

Gene Therapy00:59

Gene Therapy

25.0K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
25.0K

Articles linked to this work by shared authors, journal, and citation graph.

Cell-based therapies for malignant glioma.

Stem cells translational medicine·2026

Anti-biofilm and anti-virulence properties of Ricinus communis and Catharanthus roseus leaves against Pseudomonas aeruginosa PAO1.

In vitro models·2026

Decentralized graph attention multi-agent reinforcement learning for adaptive urban traffic routing.

Scientific reports·2026

Neural stem cell delivery of oncolytic CRAd-S-pk7 immunotherapy for stage 3 ovarian cancer: Dose-regimen studies.

Molecular therapy. Oncology·2026

Machine learning-based academic performance prediction with explainability for enhanced decision-making in educational institutions.

Scientific reports·2025

PD-L1 Inhibitor Cosibelimab for Cutaneous Squamous Cell Carcinoma: Comprehensive Evaluation of Efficacy, Mechanism, and Clinical Trial Insights.

Biomedicines·2025

Rapid in vivo screening of tumor-targeting aptamers using zebrafish larvae.

Molecular therapy. Nucleic acids·2026

cGAS-mediated immunogenicity impairs the stability and safety of LNP-encapsulated DNA in vivo.

Molecular therapy. Nucleic acids·2026

Systemic and local delivery of siRNA to the CNS and periphery via anti-IGF1R antibody conjugation.

Molecular therapy. Nucleic acids·2026

Genome-wide CRISPRa screens identify modulators of CAR T survival across diverse tumor cytokine milieus.

Molecular therapy. Nucleic acids·2026

Morpholino-mediated splice switching of NELFE suppresses hepatocellular carcinoma cell phenotypes in vitro and in vivo.

Molecular therapy. Nucleic acids·2026

Targeting miR-21 ameliorates colitis by restoring Th17/Treg balance through direct inhibition of Smad7/Ski.

Molecular therapy. Nucleic acids·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us