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Updated: May 20, 2025
Immunophenotyping and Cell Sorting of Human MKs from Human Primary Sources or Differentiated In Vitro from Hematopoietic Progenitors
Published on: August 7, 2021
[Anaplasmosis imitating haematological disease with hyperinflammation]
Christian S Benson1, Anders Porskrog1, Rune Stensvold2
1Infektionsmedicinsk Afsnit, Sjællands Universitetshospital, Roskilde.
Abstract:
Anaplasmosis is caused by the tick-borne bacterium Anaplasma phagocytophilum. In this case report, a 73-year-old immunocompetent male was admitted with high fever, headache and fatigue following a tick bite. The patient had hyperinflammation and an intense 18F-fluordeoxyglucose uptake in the spleen and bone marrow. The patient's symptoms subsided without specific treatment. A. phagocytophilum was identified by use of amplicon-based 16S/18S rDNA next generation-sequencing of DNA extracted from ethylenediamine tetraacetic (EDTA) blood. This test may serve a role in the diagnosis of fever following tick bite in the future.
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