Related Experiment Video

Updated: Jul 28, 2026

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

[Myocardial infarct in rheumatic mitral valve defects]

A D Khetagurov, S I Saksonov

    Terapevticheskii Arkhiv
    |January 1, 1985
    PubMed

    Insights

    Rheumatic heart disease rarely causes myocardial infarction. When it does, it is linked to coronary heart disease due to atherosclerosis, not the rheumatic process itself.

    Area of Science:

    • Cardiology
    • Pathology

    Background:

    • Rheumatic heart disease (RHD) is a significant global health concern.
    • Myocardial infarction (MI) is a leading cause of mortality worldwide.

    Observation:

    • Analysis of clinical and autopsy findings revealed RHD is rarely associated with MI (0.8%).
    • Extensive transmural MI in RHD patients was observed exclusively in conjunction with coronary heart disease (CHD).

    Findings:

    • Extensive myocardial infarction in RHD is primarily conditioned by coronary atherosclerosis (CHD), not the rheumatic process.
    • MI in RHD patients typically presents with common clinico-electrocardiographic features characteristic of CHD.

    Implications:

    • Understanding the underlying cause of MI in RHD patients is crucial for accurate diagnosis and treatment.
    • This highlights the importance of managing coronary atherosclerosis in patients with RHD to prevent severe cardiac events.

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