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Updated: May 20, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Hospital Clinicians' Knowledge of and Opportunity and Motivation for Prescribing Short Antibiotic Courses for Common
Michael Wilcock1, Dan Hearsey1, Mandy Slatter2
1Pharmacy Department, Royal Cornwall Hospitals NHS Trust, Truro TR1 3LJ, UK.
Abstract:
Short-course antibiotic therapies for common infections treated in hospital are supported by national guidelines. Hospital clinicians' knowledge of the course length recommendations for the management of common infections has not been fully explored. This study aims to assess doctors' knowledge of and explores their opportunity and motivation for prescribing short-course therapy. A survey was emailed to all prescribers working in adult medical specialties in two hospitals in England. The survey responses from both hospitals were pooled before analysis. One hundred and sixty-five responses were provided. Knowledge of the recommended short course lengths was high overall, except for severe community-acquired/hospital-acquired pneumonia (CAP/HAP), with only 44% of respondents opting for shorter-course therapy. The majority did not believe longer courses were more effective than shorter courses. We identified a gap in prescriber knowledge for appropriate antibiotic course lengths for severe CAP/HAP. Addressing this gap may contribute to antimicrobial stewardship efforts to reduce course lengths in line with national guidelines.
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