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Frontal Lobe Herniation After Endoscopic Anterior Skull Base Resection: A Rare Complication
Skander Kedous1, Khaled Radhouane2, Ameni Amri1
1Ears Nose and Throat, Head and Neck Surgery Department, Salah Azaiz Institute, Tunis, Tunisia.
Ear, Nose, & Throat Journal
|March 24, 2025
Summary
Cerebral herniation is a rare complication following endoscopic skull base surgery. This case highlights multifactorial causes, including meningitis, emphasizing the need for careful patient management.
Area of Science:
- Neurosurgery
- Otolaryngology
- Oncology
Background:
- Sinonasal tumors are rare head and neck cancers.
- Endoscopic surgery offers advantages over open approaches but carries risks.
- Cerebral herniation is an underreported complication after endoscopic skull base surgery.
Purpose of the Study:
- To present a case of frontal lobe herniation after endoscopic resection of esthesioneuroblastoma.
- To explore the pathophysiology and management challenges of this rare complication.
- To underscore the importance of multifactorial assessment for optimizing patient outcomes.
Main Methods:
- Case report of a 33-year-old male patient.
- Endoscopic resection of an olfactory esthesioneuroblastoma.
- Analysis of potential contributing factors to cerebral herniation, including meningitis and elevated intracranial pressure.
Main Results:
- The patient developed frontal lobe herniation post-operatively.
- Meningitis and elevated intracranial pressure were identified as potential contributing factors.
- The case highlights the complexity of managing cerebral herniation after endoscopic skull base procedures.
Conclusions:
- Cerebral herniation, though rare, is a significant complication of endoscopic anterior skull base surgery.
- Multifactorial causes, including infection and increased intracranial pressure, must be considered.
- Preoperative identification of risk factors is crucial for optimizing management and improving patient outcomes.

