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The Swiss Transplant Cohort Study: Implications for Transplant Infectious Diseases Research
Christian van Delden1, Oriol Manuel2, Cédric Hirzel3
1Transplant Infectious Diseases Unit, Service of Infectious Diseases, University Hospitals Geneva, University of Geneva, Geneva, Switzerland.
Summary
The Swiss Transplant Cohort Study (STCS) tracks transplant recipients, collecting data on outcomes and infectious diseases. This large, long-term study provides real-world insights and supports clinical trials for better patient care.
Area of Science:
- Transplantation research
- Epidemiology
- Infectious diseases in transplant recipients
Background:
- The Swiss Transplant Cohort Study (STCS) is a nationwide, longitudinal study.
- It follows over 92% of all transplant recipients in Switzerland.
- Comprehensive data collection focuses on overall and organ-specific transplant outcomes.
Purpose of the Study:
- To provide a unique platform for understanding real-world epidemiology in transplanted patients.
- To support observational analyses and randomized controlled trials.
- To highlight the achievements and future directions of the STCS.
Main Methods:
- Longitudinal, nationwide cohort study design.
- Comprehensive data collection on transplant recipients.
- Infectious disease event assembly by transplant ID specialists using common definitions.
Main Results:
- Over 6000 active patients with a median follow-up exceeding 6 years.
- Established a robust dataset for transplant outcome research.
- Facilitated the study of transplant infectious diseases.
Conclusions:
- The STCS is a valuable resource for transplant research.
- It offers unique insights into real-world transplant epidemiology.
- Future directions include continued data collection and support for clinical trials.

