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A case report of giant retroperitoneal liposarcoma
Zicheng Bao1, Nan Jia, Zhidong Zhang
1Third Department of Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Medicine
|March 24, 2025
Summary
This case study details the successful surgical management of a giant retroperitoneal liposarcoma in a young male. It underscores the importance of precise surgical techniques and multidisciplinary care for optimal outcomes in rare, complex malignancies.
Area of Science:
- Oncology
- Surgical Oncology
- Radiology
Background:
- Retroperitoneal liposarcoma (RPLS) is a rare cancer with a high recurrence rate.
- Giant RPLS (≥30 cm) presents significant surgical challenges due to its size and potential invasion of vital organs.
- Effective management of RPLS in young patients requires early diagnosis and a multidisciplinary approach.
Purpose of the Study:
- To highlight the complexities and successful management of a giant retroperitoneal liposarcoma in a young adult.
- To emphasize the critical role of surgical precision and collaborative care in managing large, invasive tumors.
- To underscore the importance of comprehensive preoperative evaluation and standardized postoperative care.
Main Methods:
- A 36-year-old male presented with abdominal distension caused by a massive tumor.
- Diagnostic workup included imaging studies to evaluate the giant retroperitoneal liposarcoma.
- Surgical intervention involved tumor resection, partial colectomy, ureterostomy, and adhesiolysis.
Main Results:
- The patient was discharged 14 days postoperatively without immediate complications.
- Postoperative albumin levels normalized within one month.
- Five-year follow-up showed no evidence of tumor recurrence on abdominal ultrasound.
Conclusions:
- Giant retroperitoneal liposarcomas often invade surrounding tissues, necessitating thorough preoperative assessment.
- Multidisciplinary collaboration, precise surgical techniques, and standardized perioperative management are crucial for improving resection rates and minimizing recurrence.
- This case demonstrates the feasibility of successful surgical resection and long-term disease control for giant RPLS.

