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Updated: May 20, 2025

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Elevated serum pre-arrest cathepsin D concentrations are associated with higher mortality in in-hospital cardiac

Taline Lazzarin1, Paula Schmidt Azevedo2, Leonardo Antonio Mamede Zornoff2

  • 1Internal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Rubião Junior S/N, Botucatu, SP, 18618-970, Brazil. taline.lazzarin@unesp.br.

Critical Care (London, England)
|March 25, 2025
PubMed
Abstract

No abstract available in PubMed .

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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Cardiac myocytes produce these hormones in response to ventricular stretching...
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