Gastric inverted polyp successfully resected by underwater endoscopic mucosal resection

Area of Science:

• Gastroenterology
• Gastrointestinal Endoscopy
• Surgical Pathology

Background:

• Subepithelial lesions of the stomach require careful monitoring and diagnosis.
• Gastric inverted polyps can present with concerning features like central depression.

Purpose of the Study:

• To diagnose and manage a growing gastric subepithelial lesion.
• To highlight the diagnostic and therapeutic approach for gastric inverted polyps.

Main Methods:

• Annual esophagogastroduodenoscopy and endoscopic ultrasonography.
• Underwater endoscopic mucosal resection for en bloc biopsy.
• Histopathological examination for definitive diagnosis.

Main Results:

• A gastric subepithelial lesion grew to over 10 mm with central depression over 11 years.
• Endoscopic ultrasonography showed a lesion originating from the second layer with low echogenicity.
• Histopathology confirmed a gastric inverted polyp, necessitating resection.

Conclusions:

• Gastric inverted polyps with central depression or erosion have malignant potential.
• Endoscopic resection is the recommended treatment for such gastric lesions.
• Long-term surveillance is crucial for gastric subepithelial lesions.