Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioplastics

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Distinct Risk Profiles for Intraoperative Blood Loss and Perioperative Transfusion in Colorectal Cancer: A Comparative Predictive Modelling Study.

ANZ journal of surgery·2026

Same author

Which immunonutritional marker best predicts disease-free survival in non-metastatic colorectal Cancer? The CALLY index and CAR emerge as independent predictors from a seven-marker comparison.

Frontiers in nutrition·2026

Same author

Network Analysis of Sleep, Mental Health, and Stress in Korean Dentists.

International dental journal·2026

Same author

Synovial Fluid Biomarkers Reflect Pre- and Postoperative Clinical Features in Rotator Cuff Tears, Independent of Tear Size.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026

Same author

Deep learning for automatic segmentation of the inferior alveolar nerve using a hybrid CNN-transformer framework.

Scientific reports·2026

Same author

Evaluation of Protective Efficacy of Formalin-Killed and Auxotrophic-Live Vibrio anguillarum Against Homologous and Heterologous Strains in Rainbow Trout (Oncorhynchus mykiss).

Journal of fish diseases·2026

Search research articles

Related Experiment Video

Updated: Apr 30, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

Enhancing Biodegradable Bone Plate Performance: Stereocomplex Polylactic Acid for Improved Mechanical Properties and

Su Jeong Park^1,2, Ho-Kyung Lim³, Sung-Jae Lee⁴

¹NBIT, KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.

Biomacromolecules

|March 25, 2025

Summary

New biodegradable bone plates made from stereocomplex polylactic acid (scPLA) show improved strain resistance and mechanical properties. These advanced scPLA plates offer promising orthopedic applications with comparable bone healing to existing PLLA plates.

More Related Videos

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

Related Experiment Videos

Last Updated: Apr 30, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

Area of Science:

Biomaterials Science
Orthopedic Engineering
Polymer Chemistry

Background:

Biodegradable bone plates offer advantages in orthopedic fixation but are often limited by brittleness.
Patient-specific treatments are crucial in orthopedics, necessitating advanced material solutions.

Purpose of the Study:

To fabricate and evaluate bone plates using stereocomplex polylactic acid (scPLA).
To analyze the impact of poly(d-lactic acid) molecular weight and scPLA blending ratios on material properties.
To assess the mechanical, optical, and in vivo bone-healing performance of scPLA bone plates.

Main Methods:

Fabrication of bone plates using stereocomplex polylactic acid (scPLA).
Analysis of poly(d-lactic acid) molecular weight and scPLA blending ratios.
Mechanical testing (modulus, strain resistance, elongation).
Optical property assessment (transparency).
In vivo comparison with commercial poly(l-lactic acid) (PLLA) bone plates.

Main Results:

scPLA bone plates demonstrated improved strain resistance and enhanced elongation compared to poly(l-lactic acid) (PLLA).
Enhanced mechanical properties were attributed to tie molecules within the scPLA structure.
scPLA bone plates showed improved transparency in optical and near-infrared ranges and smaller crystallite size.
No significant differences in in vivo bone-healing ability were observed compared to commercial PLLA plates.

Conclusions:

Stereocomplex polylactic acid (scPLA) offers superior mechanical and optical properties for bone plate applications.
The biocompatibility and enhanced characteristics of scPLA suggest significant potential for orthopedic diagnostics and therapeutics.
scPLA represents a viable alternative to conventional PLLA for bone fixation with comparable healing outcomes.