Geriatric assessment domains as predictors for clinical endpoints in older adults with cancer: Protocol for an updated systematic review
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View abstract on PubMed
Summary
This summary is machine-generated.Geriatric assessments (GA) help older cancer patients by predicting mortality and treatment outcomes. Identifying key GA domains can improve risk stratification when full assessments aren't feasible.
Area Of Science
- Geriatric Oncology
- Evidence-Based Medicine
- Systematic Review Methodology
Background
- Geriatric assessments (GA) are crucial for guiding treatment decisions and supportive care in older adults with cancer.
- Identifying specific GA domains that predict outcomes is essential for risk stratification, especially when comprehensive assessments are not feasible.
Purpose Of The Study
- To systematically review and evaluate individual geriatric assessment domains as predictors of mortality and treatment-related outcomes in older adults with cancer.
- To inform the optimization of geriatric assessments for improved patient management and outcomes.
Main Methods
- Updated systematic review of peer-reviewed literature from July 2017 onwards.
- Searches conducted in Medline, Cochrane, Embase, and CINAHL databases using a predefined strategy.
- Independent screening, data extraction by at least two authors, and assessment of cut-offs for GA domains.
Main Results
- The review will synthesize evidence on the predictive value of individual GA domains for mortality and treatment outcomes.
- Analysis will consider heterogeneity, variability in GA tools/cutoffs, and risk of bias.
- A meta-analysis will be performed if criteria for heterogeneity and data availability are met.
Conclusions
- Individual geriatric assessment domains can serve as valuable predictors for mortality and treatment outcomes in older cancer patients.
- Findings will guide the refinement of geriatric assessment protocols to enhance risk stratification and personalize care for this population.
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