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Updated: Jul 19, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
Cubosomes-based hydrogels; A promising advancement for drug delivery
Sara Khoshdooz1, Parisa Khoshdooz1, Reihaneh Bonyad1
1Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran; Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Abstract:
Hydrogels have so far shown promising opportunities for possible drug delivery applications. Cubosomes (Cub), bicontinuous cubic phase liquid crystals, possess several characteristics that make them appealing as a versatile medium for drug administration. They have been regarded as prospective nanocarriers for drugs, offering a promising alternative to liposomes as a drug delivery method. Cub have the ability to encapsulate lipophilic, hydrophilic, and amphiphilic medicines. Hydrogels have recently shown significant interest in using Cub-based formulations. This paper examines the current advancements in biodegradable Cub-based hydrogels (Cubogel) for intelligent medication delivery to various organs. In conclusion, this paper briefly discusses the prospects and problems of hydrogels based on Cub.
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