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Pontine tuberculoma presenting as a true-localising abducens palsy
Sripathi Kamath B1, Madhurima A Nayak2, Geover Joslen Lobo3
1Ophthalmology, Father Muller Medical College, Mangalore, Karnataka, India.
An immunocompetent woman in her early 30s presented with a 3-day history of nausea, vomiting and horizontal diplopia. Examination revealed left-sided abducens paresis, with normal visual acuity, pupillary reactions and fundus. There was no papilloedema, neck rigidity or positive neurological signs. Magnetic resonance imaging (MRI) showed a central pontine T2 hypointense ring-enhancing lesion causing compression of the fourth ventricle. Magnetic resonance spectroscopy showed a lipid lactate peak leading to a diagnosis of pontine tuberculoma. The diagnosis was supported by a positive Mantoux and interferon-gamma release assay. There was no other systemic focus of tuberculosis. She was then started on antitubercular therapy (ATT) for 18 months. After 8 months of ATT, a repeat MRI showed a decrease in the volume of the tuberculoma. This case exemplifies a unique case of isolated abducens palsy in the absence of features of raised intracranial tension, which could localise the lesion to the pons.
An immunocompetent woman in her early 30s presented with a 3-day history of nausea, vomiting and horizontal diplopia. Examination revealed left-sided abducens paresis, with normal visual acuity, pupillary reactions and fundus. There was no papilloedema, neck rigidity or positive neurological signs. Magnetic resonance imaging (MRI) showed a central pontine T2 hypointense ring-enhancing lesion causing compression of the fourth ventricle. Magnetic resonance spectroscopy showed a lipid lactate peak leading to a diagnosis of pontine tuberculoma. The diagnosis was supported by a positive Mantoux and interferon-gamma release assay. There was no other systemic focus of tuberculosis. She was then started on antitubercular therapy (ATT) for 18 months. After 8 months of ATT, a repeat MRI showed a decrease in the volume of the tuberculoma. This case exemplifies a unique case of isolated abducens palsy in the absence of features of raised intracranial tension, which could localise the lesion to the pons.

