Related Experiment Video
Updated: May 20, 2025

Construction of a Realistic, Whole-Body, Three-Dimensional Equine Skeletal Model using Computed Tomography Data
Published on: February 25, 2021
Navicular avascular necrosis in juvenile idiopathic arthritis
Vaibhav S Bellary1, Jitendra Shankarlal Oswal2, Deepti Agarwal1
1Department of Clinical Immunology and Rheumatology, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune, Maharashtra, India.
Abstract:
We present a case of a child in middle childhood (6-11 years) diagnosed with juvenile idiopathic arthritis (JIA) who developed glucocorticoid-induced avascular necrosis (AVN) of the navicular bone. Glucocorticoid-induced AVN in children, particularly of the navicular bone, is a rare but serious complication. Glucocorticoid therapy, often used in managing JIA, can disrupt the blood supply to developing bones, leading to AVN. Early recognition and intervention are crucial to prevent long-term morbidity. This case underscores the importance of minimising the duration of prolonged glucocorticoid use in children.
Related Concept Videos
Ankle Joint
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Bones of the Upper Limb: Radius
The radius has a nail-shaped head, and a...
Bones of the Upper Limb: Ulna
Bones of the Upper Limb: Humerus

