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Updated: May 20, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Iridium-Catalyzed, Copper-Induced Reductive Cyclization of NO2-Pyrrolarenes with CO2 as a Single-Carbon Source
Qiang Yan1, Jiang Nan1,2, Lanxin Zhu1
1College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China.
Abstract:
A new catalytic conversion type of nitro substrate with CO2 as a single-carbon source is presented, wherein a great collection of azaheterocycles is generated by a newly established iridium-catalyzed, copper-induced reductive system. This catalytic procedure handily employs poly(methylhydrosiloxane) (PMHS) as the reductant to simultaneously realize the dual reduction of the highest oxidation-state nitro and CO2 units in one operation. Elaborate mechanistic studies illustrate the essential role of the iridium catalyst in reducing the NO2 moiety as well as the double functions of the copper additive in the subsequent formylation and C-H cyclization steps.
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