Related Experiment Video
Updated: May 20, 2025
09:31
Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
Published on: February 27, 2018
11.7K
Mechanical versus kinematic alignment for total knee arthroplasty: a meta-analysis
Filippo Migliorini1,2, Nicola Maffulli3,4,5, Marco Pilone6
1Department of Orthopedics and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA), 39100, Bolzano, Italy. migliorini.md@gmail.com.
Archives of Orthopaedic and Trauma Surgery
|March 26, 2025
Summary
This meta-analysis found no significant differences in patient-reported outcomes or revision rates between mechanical and kinematic alignment in total knee arthroplasty (TKA). A slight increase in range of motion (ROM) was observed with kinematic alignment, but it lacked clinical significance.
Area of Science:
- Orthopedic Surgery
- Biomechanical Engineering
Background:
- Total knee arthroplasty (TKA) aims to restore function and alleviate pain.
- Alignment techniques, including mechanical and kinematic, influence TKA outcomes.
- Patient-reported outcome measures (PROMs), range of motion (ROM), and revision rates are key indicators of TKA success.
Purpose of the Study:
- To compare mechanical versus kinematic alignment in TKA.
- To evaluate the impact of alignment on PROMs, ROM, and revision rates.
Main Methods:
- Systematic review and meta-analysis adhering to the 2020 PRISMA statement.
- Comprehensive literature search across PubMed, Web of Science, Google Scholar, and Embase.
- Inclusion of 30 studies involving 3133 TKAs with a mean follow-up of 30.8 months.
Main Results:
- No statistically significant differences were found in PROMs, including KSS, VAS, WOMAC, and OKS.
- The revision rate did not differ significantly between the two alignment groups (P=0.4).
- A statistically significant, yet minimal, increase in ROM was observed in the kinematic alignment group (P<0.0001).
Conclusions:
- Mechanical and kinematic alignment in TKA yield comparable results regarding PROMs and revision rates.
- While kinematic alignment showed a slight improvement in ROM, this difference is unlikely to be clinically relevant.
- The choice between mechanical and kinematic alignment may not significantly impact patient outcomes in TKA.
