Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sex-linked Disorders01:43

Sex-linked Disorders

99.2K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
99.2K
Autoimmune Disorders01:29

Autoimmune Disorders

363
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
363
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

202
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
202
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

138
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
138
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

641
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
641
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

101
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
101

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long term risk of recurrence of ptosis repair: implications for surgical counseling and follow-up.

Frontiers in ophthalmology·2026
Same author

Optimizing surgical margins in the treatment of eyelid Merkel cell carcinoma: a tertiary center experience and literature review.

Frontiers in ophthalmology·2026
Same author

Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy - Case Series and Extended Features.

Retinal cases & brief reports·2025
Same author

Wait times in pediatric ophthalmology clinics: Insights from a tertiary university hospital.

European journal of ophthalmology·2025
Same author

Real-life efficacy and safety of oral propranolol for ocular adnexal infantile hemangiomas: observational cohort study.

Frontiers in ophthalmology·2025
Same author

A deep learning strategy to identify cell types across species from high-density extracellular recordings.

Cell·2025

Related Experiment Video

Updated: May 20, 2025

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
11:53

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome

Published on: May 10, 2022

3.5K

[VOGT-KOYANAGI-HARADA SYNDROME].

Dana Cohen1, Yael Ben-Arie-Weintrob2, Tamar Hareuveni-Blum3

  • 1Department of Ophthalmology, Galilee Medical Center, Nahariya.

Harefuah
|March 26, 2025
PubMed
Summary

Vogt-Koyanagi-Harada (VKH) syndrome, an autoimmune disease, can cause severe vision loss. Early diagnosis and treatment with steroids, immunosuppressants, and biologics are crucial for managing VKH complications.

More Related Videos

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV

Published on: September 14, 2010

12.5K
Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

10.9K

Related Experiment Videos

Last Updated: May 20, 2025

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
11:53

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome

Published on: May 10, 2022

3.5K
Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV

Published on: September 14, 2010

12.5K
Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

10.9K

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Vogt-Koyanagi-Harada (VKH) syndrome is a rare autoimmune disorder causing pan-ocular inflammation.
  • It can lead to systemic symptoms like hearing loss and neurologic issues.
  • Chronic inflammation and flare-ups can cause significant vision loss.

Purpose of the Study:

  • To present a case report and literature review of Vogt-Koyanagi-Harada syndrome.
  • To discuss ocular and systemic manifestations, diagnosis, and treatment.
  • To highlight the importance of early intervention in VKH.

Main Methods:

  • Case report of a 14-year-old patient with bilateral granulomatous uveitis.
  • Comprehensive workup for infectious and rheumatologic diseases.
  • Literature review on VKH manifestations, diagnosis, and treatment.

Main Results:

  • The patient initially presented with uveitis and optic nerve/retinal edema.
  • Initial steroid treatment was insufficient, with subsequent imaging confirming VKH.
  • Treatment with immunosuppressants (Imuran, Cyclosporin) and biologics showed a good response.

Conclusions:

  • Early diagnosis and prompt, appropriate treatment are vital for VKH management.
  • Multifaceted treatment including immunosuppressants and biologics can effectively control VKH.
  • Minimizing ocular and extraocular complications requires timely and aggressive therapeutic strategies.