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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: May 20, 2025

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Subnuclear Phacoemulsification to Reduce Corneal Injury in Nuclear Cataract Surgery: Evidence From a Randomized

Han Wang1,2, Rubing Liu1,2, Rong Wang3,4,5

  • 1National State Key Laboratory, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, China.

Journal of Ophthalmology
|March 26, 2025
PubMed
Summary

Subnuclear phacoemulsification (SNP) offers improved visual acuity and reduced corneal injury compared to conventional phacoemulsification (CP) in cataract surgery. This new technique enhances patient outcomes, particularly for hard nuclear cataracts.

Keywords:
cataractcorneal endothelial cellsrandomized controlled trial (RCT)subnuclear phacoemulsificationsurgical trial

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Corneal Health

Background:

  • Cataract surgery aims to restore vision but can cause corneal injury.
  • Conventional phacoemulsification (CP) carries risks of endothelial cell loss and corneal swelling.
  • New techniques are needed to minimize trauma during cataract surgery, especially for dense nuclei.

Purpose of the Study:

  • To evaluate the safety and effectiveness of subnuclear phacoemulsification (SNP) versus CP.
  • To assess SNP's impact on corneal injury and visual outcomes.
  • To compare complication rates between SNP and CP for hard nuclear cataracts.

Main Methods:

  • A randomized controlled trial (RCT) involving 256 patients with hard nuclear cataracts.
  • Patients were randomized to either SNP (experimental) or CP (control).
  • Outcomes measured included cumulative dissipated energy, ultrasound time, complications, visual acuity, central corneal thickness, and endothelial cell density.

Main Results:

  • Both groups showed comparable safety profiles regarding energy, time, and complications.
  • The SNP group demonstrated superior visual acuity and thinner central corneas within one week post-surgery.
  • Higher central corneal endothelial cell density was observed in the SNP group at 1 and 3 months.

Conclusions:

  • Subnuclear phacoemulsification (SNP) is more effective than conventional phacoemulsification (CP) in reducing corneal injury.
  • SNP offers improved visual outcomes and better preservation of corneal endothelial cells.
  • Widespread adoption of SNP can enhance cataract surgery safety, particularly for hard cataracts.