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Microangiopathic Hemolytic Anemia as paraneoplastic syndrome secondary to Pheochromocytoma: a rare case report
Omar Q Heih1, Mahmoud R Manasra1, Ziad F Salah1
1Faculty of Medicine, Palestine Polytechnic University, Wadi Hariya Campus, Hebron, Palestine.
Pheochromocytoma is a rare adrenal tumor that secretes catecholamines. Microangiopathic hemolytic anemia, a kind of hemolytic anemia in which erythrocytes are destroyed in microscopic blood capillaries, resulting in fragmentation and hemolysis. This condition is an uncommon but significant consequence observed most commonly in malignant pheochromocytoma. In this case report, we present a 21-year-old single female with a strong family history of endocrine malignancy. She was referred to our hospital for chemotherapy due to a diagnosis of malignant pheochromocytoma, which had metastasized to the urinary bladder, bone, and lung. Additionally, she developed microangiopathic hemolytic anemia as a paraneoplastic syndrome.
Pheochromocytoma is a rare adrenal tumor that secretes catecholamines. Microangiopathic hemolytic anemia, a kind of hemolytic anemia in which erythrocytes are destroyed in microscopic blood capillaries, resulting in fragmentation and hemolysis. This condition is an uncommon but significant consequence observed most commonly in malignant pheochromocytoma. In this case report, we present a 21-year-old single female with a strong family history of endocrine malignancy. She was referred to our hospital for chemotherapy due to a diagnosis of malignant pheochromocytoma, which had metastasized to the urinary bladder, bone, and lung. Additionally, she developed microangiopathic hemolytic anemia as a paraneoplastic syndrome.
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