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Mechanical Micronization of Lipoaspirates for Regenerative Therapy
Published on: March 15, 2019
Biostimulatory Fillers to Treat Post-liposuction Skin Irregularities
Stefania Guida1, Ilaria Proietti2, Claudio Conforti3
1Dr. Guida is with the School of Medicine at Vita-Salute San Raffaele University in Milan, Italy, and the Dermatology Clinic at IRCCS San Raffaele Hospital in Milan, Italy.
Background:
Treatment of post-liposuction skin irregularities (PLSI), a complication of liposuction, can be challenging.
Objective:
Considering the increasing request of treatment of PLSI, the aim of this study is to evaluate the efficacy and safety of CaHA diluted/hyperdiluted to PLSI.
Methods:
A retrospective study on a total of eight PLSI areas in six women treated with CaHA diluted/hyperdiluted was performed. Efficacy was estimated on pictures of affected areas collected before and four months after treatment, according to the recently validated PLSI scale and Student's t-test for paired samples was performed to analyze data. Eventual adverse events were used to evaluate safety.
Results:
Our results showed a statistically significant improvement of number and depth of depressions and a trend toward reduction of skin laxity.
Conclusion:
This study reported the efficacy and safety of CaHA diluted/hyperdiluted for PLSI treatment. Larger studies are encouraged to support the results of this pilot study.

