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Updated: May 20, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Rethinking arterial hypertension: the need for a paradigm shift
Gian Paolo Rossi1, Domenico Bagordo2,3, Federico Bernardo Rossi2,3
1Specialized Hypertension Center, Department of Medicine DIMED, Univerisity of Padua, Padua Italy.
Essential hypertension is often overdiagnosed, masking potentially curable secondary hypertension. Increased awareness and systematic investigation of secondary causes can lead to better blood pressure control and improved patient outcomes.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Background:
- Essential hypertension is paradoxically labeled the primary cause of arterial hypertension despite unknown etiology.
- This diagnostic approach leads to secondary hypertension being overlooked, hindering potential cures and necessitating lifelong treatment.
Purpose of the Study:
- To critically evaluate the historical development and current scientific evidence supporting the high prevalence of essential hypertension.
- To examine the concept of secondary hypertension and establish criteria for its diagnosis.
Main Methods:
- Review of scientific literature and recent studies on hypertension etiology.
- Analysis of diagnostic criteria for differentiating essential and secondary hypertension.
Main Results:
- Evidence suggests that secondary hypertension is more prevalent than commonly believed when systematically investigated.
- Current diagnostic practices may lead to underdiagnosis of secondary hypertension.
Conclusions:
- Increased awareness and systematic screening for secondary hypertension are crucial.
- Identifying and treating secondary hypertension can offer a cure or improved management, enhancing patient quality of life.
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