Related Experiment Video
Updated: Jul 6, 2026

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall
Published on: July 31, 2015
Feasibility and validation of a synthetic airway model for in situ laser dissection
Thomas Daniel Milner1, Jiak-Ying Tan2, Elaine Baird3
1Department of Otolaryngology, Queen Elizabeth University Hospital, Glasgow, UK.
Background:
This study measured the effectiveness of an in-house designed, cast silicone airway model in addressing the lack of easily accessible, validated transoral laser microsurgery simulation models.
Methods:
Participants performed resection of two marked vocal fold lesions on the model. The model underwent face, content and construct validation assessment using a five-point Likert scale questionnaire measuring the mean resection time for each lesion and the completeness of lesion excision. Comparative analyses were performed for these measures.
Results:
Thirteen otolaryngologists participated in this study. The model achieved validation threshold on all face and content measures (median, ≥4). Construct validation was demonstrated by the improvement in mean resection time between lesions one and two (86 vs 54 seconds, W = 11, p = 0.017). The mean resection time was lower amongst more senior otolaryngologists (61.5 vs 107.1 seconds, W = 11, p = 0.017).
Conclusion:
This synthetic silicone model is a low-cost, easily reproducible, high-fidelity synthetic airway model, demonstrating face, content and construct validity.
Related Concept Videos
Flame Photometry: Overview
Typical Model Studies

