[Coarctation of the aortic isthmus in the adult]
Related Experiment Videos
Insights
Coarctation of the aorta surgery in adults often leads to persistent hypertension, with many patients remaining symptomatic. Early diagnosis and treatment are crucial for better outcomes in coarctation of the aorta patients.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Adult Congenital Heart Disease
Context:
- Coarctation of the aorta (CoA) is a congenital heart defect.
- Surgical repair is the standard treatment for CoA.
- Long-term outcomes after CoA repair require further investigation.
Purpose:
- To evaluate the long-term outcomes of adult patients who underwent surgical repair for coarctation of the aorta.
- To assess the prevalence of hypertension and functional symptoms post-surgery.
Summary:
- This study followed 44 adult patients operated on for coarctation of the aorta between 1962 and 1983.
- Hypertension was prevalent (86%), with 31% experiencing drug-resistant hypertension during a mean follow-up of 13 years.
- Late deaths occurred in 3 patients, and 18% reported functional symptoms.
Impact:
- The findings highlight the significant long-term morbidity associated with coarctation of the aorta, particularly persistent hypertension.
- Emphasizes the critical need for early diagnosis and timely intervention to improve patient prognosis.
- Informs clinical practice regarding lifelong monitoring and management of adult congenital heart disease patients.
Abstract:
Forty four patients over the age of eighteen operated upon for coarctation of the aorta from 1962 to 1983 at our institution were followed for one to 21 years (mean 13 years 3 months). Hypertension was found in 86% of the patients and 82% were preoperatively symptomatic. There were three late deaths. During the follow-up period, drug resistant hypertension persists in 31% of the patients at rest and/or exertion and 18% have functional symptoms. These data emphasize the importance of early diagnosis and treatment for patients with coarctation of the aorta.