Impact of Personalized Recovery Interventions on Spinal Instability and Psychological Distress in Oncological Patients with Vertebral Metastases

  • 0Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.

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Summary

This summary is machine-generated.

Personalized recovery interventions significantly improved quality of life for cancer patients with vertebral metastases by reducing spinal instability and psychological distress. These tailored strategies also led to better survival and fewer complications.

Area Of Science

  • Oncology
  • Rehabilitation Medicine
  • Palliative Care

Background

  • Vertebral metastases significantly impair quality of life due to spinal instability, pain, and psychological distress.
  • Spinal Instability Neoplastic Score (SINS) quantifies instability, correlating with functional and emotional decline.
  • Personalized recovery interventions offer a potential to mitigate these adverse effects.

Purpose Of The Study

  • To investigate the impact of personalized recovery interventions on spinal instability, psychological distress, and quality of life in oncological patients with vertebral metastases.

Main Methods

  • Prospective, observational study comparing tailored rehabilitation strategies (experimental group) with standard oncological care (control group).
  • Spinal instability assessed via Spinal Instability Neoplastic Score (SINS).
  • Psychological distress measured by Hopelessness Depression Symptom Questionnaire (HDSQ); quality of life by European Quality of Life-5 Dimensions (EQ-5D).

Main Results

  • The experimental group showed significantly reduced spinal instability (lower SINS scores) and psychological distress (lower HDSQ scores).
  • Improvements observed in mobility, self-care, usual activities, and reduced anxiety/depression (EQ-5D).
  • Enhanced survival, decreased fracture rates, and lower incidence of osteoporosis, anemia, and vomiting in the experimental group.

Conclusions

  • Personalized recovery interventions enhance functional independence and emotional well-being in patients with vertebral metastases.
  • Integration of physical and psychological rehabilitation into oncological care is beneficial.
  • Further research with longitudinal, multicenter, randomized controlled trials is recommended.