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Peripheral white blood cell count in cerebral ischemic infarction
Acta Neurologica Scandinavica
|May 1, 1985
Summary
Higher white blood cell (WBC) counts in stroke patients indicate greater brain damage and poorer outcomes. This elevation reflects the acute inflammatory response following ischemic cerebral infarction.
Area of Science:
- Neurology
- Immunology
- Pathophysiology
Background:
- Ischemic cerebral infarction triggers an inflammatory response.
- The role of peripheral white blood cell (WBC) count in acute stroke is not fully understood.
Purpose of the Study:
- To investigate the relationship between peripheral WBC count and stroke severity.
- To determine if WBC count correlates with infarct size and clinical outcome.
Main Methods:
- Peripheral WBC count was measured in 95 ischemic cerebral infarction patients.
- Measurements were taken 3 days after stroke onset.
- WBC counts were correlated with neurological impairment, infarct size, and clinical outcomes.
Main Results:
- Higher WBC counts were observed in patients with severe neurological impairment.
- Increased WBC counts correlated with larger infarct size.
- A significant relationship was found between elevated WBC count and poor clinical outcome.
Conclusions:
- Peripheral WBC count elevation post-stroke reflects the acute inflammatory response.
- WBC count appears to be a marker for the extent of cerebral damage.
- Higher WBC counts are associated with worse clinical outcomes in ischemic stroke.