Related Experiment Video
Updated: May 20, 2025
16:20
Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation
Published on: July 2, 2018
18.5K
Development and Characterization of Cannabidiol Gummy Using 3D Printing
Arvind Bagde1, Mina Messiha1, Mandip Singh1
1Pharmaceutical Sciences Department, Florida A&M University, Tallahassee, FL 32307, USA.
Gels (Basel, Switzerland)
|March 26, 2025
Summary
3D printing creates customized cannabidiol (CBD) gummies for geriatric pain management. These novel gummies offer optimized drug release and improved elasticity compared to traditional molded options, enhancing patient care.
Area of Science:
- Pharmaceutical Technology
- Geriatric Medicine
- Cannabinoid Science
Background:
- Oropharyngeal dysphagia and pain are significant issues for the elderly.
- Existing oral medications can present challenges for geriatric patients.
- Cannabidiol (CBD) shows potential for pain management.
Purpose of the Study:
- To develop and characterize 3D-printed cannabidiol (CBD) gummies.
- To compare 3D-printed CBD gummies with commercially available molded gummies.
- To evaluate the suitability of 3D-printed gummies for geriatric pain management.
Main Methods:
- A gelatin-based CBD formulation was prepared and 3D printed using extrusion.
- Rheological properties, texture, drug content (HPLC), and in vitro dissolution were analyzed.
- Comparison was made against commercially available molded gummies.
Main Results:
- The formulation exhibited shear-thinning properties suitable for 3D printing.
- 3D-printed gummies demonstrated superior elasticity and comparable toughness to molded gummies.
- Both 3D-printed and molded gummies achieved 100% CBD release within 30 minutes at pH 1.2 and 6.8.
Conclusions:
- 3D printing technology facilitates the development of customizable CBD gummies.
- Optimized 3D-printed gummies offer a patient-friendly alternative for geriatric pain relief.
- This technology enables personalized drug delivery for enhanced geriatric care.
