Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

91
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
91

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing synthetic biology with engineered chemically inducible gene regulatory systems.

Biotechnology advances·2026
Same author

STG-DB net for athlete pose estimation and pose rational optimization in complex sports scenes.

Scientific reports·2026
Same author

CAR-M Therapy: From Concept to Clinical Translation in Solid Tumors.

Cells·2026
Same author

Mixed-species afforestation stimulates the flow and turnover of carbon and nitrogen within soil aggregates in a degraded karst ecosystem.

Journal of environmental management·2026
Same author

Investments in Childhood Community Resources and Subsequent Adult Health Outcomes.

JAMA network open·2026
Same author

Label-Free Fluorometric Split Aptasensor for the Specific Detection of Uric Acid from Xanthine and Hypoxanthine.

Analytical chemistry·2026

Related Experiment Video

Updated: May 5, 2026

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
13:15

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Published on: June 1, 2011

33.4K

Exploring Nucleic Acid Nanozymes: A New Frontier in Biosensor Development.

Keren Chen1, Zaihui Du1, Yangzi Zhang1

  • 1Food Laboratory of Zhongyuan, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.

Biosensors
|March 26, 2025
PubMed
Summary

Nucleic acid nanozymes (NANs) offer a novel catalytic approach for biosensing, merging nucleic acid and nanomaterial benefits. This review details their enzymatic activities and diverse applications in advanced sensor technologies.

Keywords:
aptamersbiosensorsenzyme-like propertiesnanozymesnucleic acids

More Related Videos

A Polyaniline-based Sensor of Nucleic Acids
07:58

A Polyaniline-based Sensor of Nucleic Acids

Published on: November 1, 2016

8.0K
Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

854

Related Experiment Videos

Last Updated: May 5, 2026

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
13:15

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Published on: June 1, 2011

33.4K
A Polyaniline-based Sensor of Nucleic Acids
07:58

A Polyaniline-based Sensor of Nucleic Acids

Published on: November 1, 2016

8.0K
Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

854

Area of Science:

  • Biochemistry
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Nucleic acids and nanozymes are gaining attention for catalytic applications.
  • Nucleic acid nanozymes (NANs) combine advantages of both fields.
  • NANs are increasingly used in biosensing platforms.

Purpose of the Study:

  • To provide a comprehensive review of recent studies on NAN-based biosensors.
  • To classify NANs based on their enzymatic activities.
  • To explore the influence of nucleic acid properties on nanozyme catalytic activity.

Main Methods:

  • Classification of NANs by six enzymatic activities: peroxidase-like, oxidase-like, catalase-like, superoxide dismutase-like, laccase-like, and glucose oxidase-like.
  • Analysis of regulatory mechanisms influencing NAN catalytic activity.
  • Systematic review of NAN applications in various sensor types.

Main Results:

  • NANs exhibit diverse enzymatic activities, including peroxidase, oxidase, and catalase-like functions.
  • Nucleic acid properties significantly modulate the catalytic efficiency of NANs.
  • NANs have demonstrated successful applications in colorimetric, fluorescent, electrochemical, SERS, and chemiluminescent sensors.

Conclusions:

  • NANs represent a significant advancement in biosensor technology.
  • Understanding NAN regulatory mechanisms is key to optimizing their performance.
  • NANs offer a versatile platform for developing next-generation biosensing applications.