Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

205
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
205
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

5.5K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.5K
Pharmacokinetic Models: Overview01:20

Pharmacokinetic Models: Overview

526
Pharmacokinetic models utilize mathematical analysis to achieve a detailed quantitative understanding of a drug's life cycle within the body. They are instrumental in simulating a drug's pharmacokinetic parameters, predicting drug concentrations over time, optimizing dosage regimens, linking concentrations with pharmacologic activity, and estimating potential toxicity.
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
526
Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

3.1K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.1K
Drug Discovery: Overview01:26

Drug Discovery: Overview

7.3K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
7.3K
Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance01:07

Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance

23
Drug transporters are critical in drug absorption, distribution, and excretion processes. They should be included in physiological-based pharmacokinetic (PBPK) models, which help predict human drug disposition. However, predicting this is challenging during drug development, especially when liver transport is involved. However, with a realistic representation of body transport processes, an accurate model may be possible.
A recent model describes pravastatin's hepatobiliary excretion,...
23

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Educators need to equip nursing students with the skills, knowledge and confidence to use generative AI effectively.

Evidence-based nursing·2026
Same author

Mepolizumab reduces healthcare resource utilization in patients with chronic rhinosinusitis with nasal polyps: a linked EMR and claims-based pre-post study.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology·2026
Same author

The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM.

Cell·2026
Same author

Real-world outcomes and corticosteroid sparing with mepolizumab for EGPA or HES.

The journal of allergy and clinical immunology. Global·2026
Same author

Simulation-based education is an effective approach to enhancing nurses' knowledge and understanding of domestic violence.

Evidence-based nursing·2026
Same author

Mepolizumab exhibits quantifiable reduction in corticosteroid-related adverse effects in severe asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026

Related Experiment Video

Updated: May 20, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

9.2K

Enhancing Rural Healthcare Accessibility: A Model for Pharmacogenomics Adoption via an Outreach-Focused Integration

Jared Silver1, Evan Forman1, David Barrett1

  • 1Ivey Business School, University of Western Ontario, London, ON N6G 0N1, Canada.

Journal of Personalized Medicine
|March 26, 2025
PubMed
Summary

Pharmacogenomics can improve patient care by tailoring medications. This study identifies barriers and proposes solutions like telemedicine to bring these precision medicine benefits to rural communities.

Keywords:
healthcare accessibilityoutreach strategiespersonalized medicinepharmacogenomicsprecision medicinerural healthcaretelemedicine

More Related Videos

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.0K
Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.6K

Related Experiment Videos

Last Updated: May 20, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

9.2K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.0K
Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.6K

Area of Science:

  • Pharmacogenomics
  • Precision Medicine
  • Rural Health

Background:

  • Pharmacogenomics offers personalized drug selection and dosage.
  • Rural populations face healthcare access barriers, limiting pharmacogenomics utilization.
  • Integrating specialized services like pharmacogenomics into rural healthcare is challenging.

Purpose of the Study:

  • Identify barriers to pharmacogenomics implementation in rural settings.
  • Assess strategies for integrating pharmacogenomics into rural healthcare systems.
  • Enhance access to precision medicine for rural patients.

Main Methods:

  • Qualitative research using semi-structured interviews with stakeholders.
  • Synthesis of secondary research through strategic frameworks.
  • Exploration of potential solutions for rural pharmacogenomics access.

Main Results:

  • Stakeholder awareness of pharmacogenomics is mixed, necessitating targeted education.
  • Mail-in testing and telemedicine are feasible solutions for geographical and logistical barriers.
  • Successful integration requires leveraging existing infrastructure and prioritizing patient care, workflow, and adoption.

Conclusions:

  • A multi-faceted approach is essential to overcome barriers for rural pharmacogenomics.
  • Outreach, education, and innovative delivery models are key to successful implementation.
  • Making pharmacogenomics viable in rural areas improves healthcare equity and patient outcomes.