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Microbial Infections and Antimicrobial Use in Neonates and Infants

Chryssoula Tzialla1

  • 1Neonatal and Pediatric Unit, Polo Ospedaliero Oltrepò, ASST Pavia, 27058 Voghera, Italy.

Tropical Medicine and Infectious Disease
|March 26, 2025
PubMed

Insights

Infectious diseases cause significant infant morbidity and mortality, contributing to one-third of neonatal deaths and half of all deaths in young children globally. Addressing these infections is critical for improving child survival rates.

Area of Science:

  • Neonatal infectious diseases
  • Pediatric infectious disease epidemiology
  • Global child health

Background:

  • Infectious diseases represent a primary threat to infant survival during the neonatal period.
  • These infections are responsible for a substantial proportion of neonatal mortality and deaths in children under five years of age.

Discussion:

  • The high burden of infectious diseases in neonates underscores the need for effective prevention and treatment strategies.
  • Understanding the epidemiology of these diseases is crucial for public health interventions.

Key Insights:

  • Infectious diseases account for approximately 33% of all neonatal deaths.
  • These diseases contribute to 50% of deaths in children under the age of five.
  • Reducing infectious disease mortality is essential for achieving global child survival goals.

Outlook:

  • Further research into novel diagnostics and therapeutics for neonatal infections is warranted.
  • Strengthening healthcare systems to manage infectious disease outbreaks in infants is a priority.
  • Global collaboration is needed to combat the impact of infectious diseases on infant mortality.

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