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Updated: Jun 23, 2026

Induction and Assessment of Ischemia-reperfusion Injury in Langendorff-perfused Rat Hearts
Published on: July 27, 2015
Beyond the Blockage: A Comprehensive Analysis of Reperfusion Injury Across Different Organs Post Endovascular
Yashaswi Singh1, Anjali Sah1, Rajendra Kumar Behera1
1Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Endovascular stenting has emerged as the gold standard for treating various occlusive vascular disorders. However, it has its own challenges. Reperfusion injury, a paradoxical tissue damage that occurs after the restoration of blood flow, is one such challenge seen with endovascular interventions. This case series presents three instances of reperfusion injury involving the carotid, superior mesenteric, and renal arteries following stenting procedures. Timely management with targeted interventions, including coil embolization and hemodynamic stabilization, was crucial in mitigating adverse outcomes. By examining these cases, this series highlights the importance of increased awareness, early recognition, and targeted interventions in order to optimize patient outcomes.Clinical ImpactReperfusion injury after endovascular stenting is a serious but often overlooked complication that can lead to life-threatening consequences. This case series highlights the need for early recognition, careful blood pressure control, and prompt intervention to prevent complications. By examining cases involving the carotid, renal, and superior mesenteric arteries, we emphasize the importance of close post-procedure monitoring and tailored treatment strategies. Raising awareness about this issue and developing better management guidelines can improve patient outcomes and make vascular interventions safer. Our findings reinforce the need for vigilance and proactive care in endovascular treatments.

