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Updated: May 20, 2025

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
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Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Published on: May 15, 2011

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Design of the First in Human Gene Therapy Trial of TLT-101 for Chronic Heart Failure (FIGHT-HF)

Pia Balmaceda1, Tara C Hitzeman2, Kikuyo E Shaw3

  • 1Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, USA; London School of Hygiene and Tropical Medicine, University of London, London, England.

JACC. Basic to Translational Science
|March 26, 2025
PubMed
Abstract

No abstract available in PubMed .

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Related Concept Videos

Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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