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Understanding and Managing Infusion Reactions and Hypophosphataemia With Intravenous Iron-A Nurses' Consensus Paper.
Aileen Fraser1, Vida Cairnes2, Else Mikkelsen3
1University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Nursing Open
|March 27, 2025
Summary
Nurses require clear guidance on administering intravenous iron safely. This consensus provides evidence-based recommendations for patient preparation, monitoring for infusion reactions, and managing hypophosphataemia to enhance patient care.
Area of Science:
- Nursing Practice
- Pharmacology
- Patient Safety
Background:
- Intravenous iron administration is common for iron deficiency anemia.
- Existing literature lacks a nursing-specific perspective on practicalities and safety concerns.
- Nurses play a central role in intravenous iron administration and patient monitoring.
Purpose of the Study:
- To offer evidence-based guidance on the practical aspects of intravenous iron administration.
- To address potential safety concerns, including infusion reactions and hypophosphataemia, from a nursing viewpoint.
- To enhance nurse confidence and ensure patient safety during intravenous iron therapy.
Main Methods:
- A modified Delphi consensus method was employed.
- Literature searches informed the development of consensus statements.
- Expert nurses in gastroenterology participated in the consensus process.
Main Results:
- Sixteen consensus statements were developed, covering administration, infusion reactions, and hypophosphataemia.
- Patient preparation and communication are crucial to prevent anxiety.
- Vigilance for hypophosphataemia symptoms and monitoring serum phosphate are recommended for specific iron formulations.
Conclusions:
- Infusion reactions and hypophosphataemia are known risks of intravenous iron.
- This consensus emphasizes patient preparation, monitoring, and prompt management for safe administration.
- Evidence-based guidance is essential for nurses administering intravenous iron.
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