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Socio-economic status is a social construct with heritable components and genetic consequences
Abdel Abdellaoui1, Hilary C Martin2, Martin Kolk3,4
1Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. a.abdellaoui@amsterdamumc.nl.
Socio-economic status (SES) is linked to genetics and social structures. Genomics research reveals how societal organization impacts gene distribution, with implications for fairness and societal function.
Area of Science:
- Sociogenomics
- Behavioral Genetics
- Social Epidemiology
Background:
- Socio-economic status (SES) clusters within families and geographically, showing a strong association with genetic effects.
- Historical scientific research has explored the intricate relationship between SES and heredity.
- Recent genomics research provides new insights into this complex interplay.
Purpose of the Study:
- To review the history of scientific research on the relationship between SES and heredity.
- To discuss recent genomics findings concerning the hypothesis that SES is a dynamic social construct.
- To explore how genetically influenced traits contribute to achieving or maintaining SES and affect gene distribution.
Main Methods:
- Literature review of historical scientific research on SES and heredity.
- Analysis of recent genomics research findings.
- Discussion of sociogenomic hypotheses and evolutionary selection pressures.
Main Results:
- SES is robustly associated with genetic effects, clustering in families and geography.
- Genetically influenced traits may play a role in achieving or retaining socio-economic positions.
- Social stratification leads to differential environmental exposures and potential evolutionary selection pressures.
Conclusions:
- Genomics research uncovers hidden genetic consequences of societal organization.
- Understanding the interplay between SES, genetics, and social structures is crucial.
- Insights should be approached cautiously to foster a fair and functional society.
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