Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Dysplastic Barrett's esophagus in scleroderma.

D J Sprung, S P Gibb

The American Journal of Gastroenterology

|July 1, 1985

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

H. pylori: is it really such a bad guy after all?

The American journal of gastroenterology·1998

Same author

What is the role of Helicobacter pylori in peptic ulcer and gastric cancer outside the big cities?

Journal of clinical gastroenterology·1998

Same author

Consensus conference on surveillance for Barrett's esophagus.

The American journal of gastroenterology·1997

Same author

Esophageal achalasia and adenocarcinoma in Barrett's esophagus: a report of two cases and a review of the literature.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·1997

Same author

Reoperation after failed antireflex surgery. Review of 101 cases.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·1996

Same author

Current status of cricopharyngeal myotomy for cervical esophageal dysphagia.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·1996

Same journal

Calendar of Courses, Symposiums and Conferences.

The American journal of gastroenterology·2026

Same journal

Molecular Nonendoscopic Tests for the Early Detection of Esophageal Squamous Carcinoma and High-Grade Dysplasia: Promising Progress.

The American journal of gastroenterology·2026

Same journal

ACG Clinical Guideline: Colonic Diverticulitis.

The American journal of gastroenterology·2026

Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026

Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026

Same journal

2026 CME Information.

The American journal of gastroenterology·2026

See all related articles

Scleroderma patients have an increased risk of Barrett's esophagus, a precancerous condition. Early detection through surveillance is crucial for managing esophageal dysplasia in these individuals.

Area of Science:

Gastroenterology
Rheumatology
Oncology

Background:

Barrett's esophagus is a premalignant condition of the esophagus.
Scleroderma is an autoimmune disease affecting connective tissue, often impacting the gastrointestinal tract.

Observation:

A review of 107 Barrett's esophagus patients identified three with coexisting scleroderma.
Two of these patients exhibited high-grade dysplasia, while one had nondysplastic changes.

Findings:

Scleroderma is associated with factors predisposing to Barrett's esophagus, including lower esophageal sphincter incompetence and reflux esophagitis.
The presence of scleroderma may increase the risk or alter the presentation of Barrett's esophagus.

Implications:

Related Experiment Videos

Patients with both scleroderma and Barrett's esophagus require vigilant endoscopic and pathological surveillance.
Aggressive medical management and monitoring are essential to prevent malignant transformation in this high-risk group.