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Fat Preference: A Novel Model of Eating Behavior in Rats
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Correction: Yin et al. Angiogenesis-Browning Interplay Mediated by Asprosin-Deficiency Contributes to Weight Loss in

Tingting Yin1,2, Sheng Chen1,2, Guohua Zeng1,2

  • 1Key Provincial Laboratory of Basic Pharmacology, Nanchang University, Nanchang 330006, China.

International Journal of Molecular Sciences
|March 27, 2025
PubMed

Abstract:

In the original publication [...].

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Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...

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