An Assessment of the Efficacy of Commercial Air Ionizer Systems Against a SARS-CoV-2 Surrogate

Nachiket Vaze1, Brittany Gold2, Douglas Lindsey3

  • 1Nanoscience and Advanced Materials Center, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854, USA.

Microorganisms
|March 27, 2025
PubMed

Insights

Two commercial air ionizers effectively reduced airborne MS2 virus, a surrogate for SARS-CoV-2, by over 80%. These findings highlight air ionizers as a potential tool to combat the spread of airborne infectious diseases.

Area of Science:

  • Environmental microbiology
  • Infectious disease control
  • Air purification technologies

Background:

  • Airborne transmission is a significant route for infectious disease spread, as highlighted by the COVID-19 pandemic.
  • There is a critical need for technologies to inactivate airborne viruses and prevent disease transmission.
  • Bacteriophage MS2 serves as a reliable surrogate for human viruses like SARS-CoV-2 and noroviruses in aerosol studies.

Purpose of the Study:

  • To evaluate the efficacy of two commercial air ionizer systems in inactivating airborne bacteriophage MS2.
  • To assess the potential of air ionizers as a tool for controlling airborne infectious agents.

Main Methods:

  • An experimental test apparatus simulating an HVAC duct system was used for efficacy testing.
  • Viral aerosols of bacteriophage MS2 were generated and exposed to two different air ionizer devices.
  • The reduction in viral concentration in the air was measured after treatment by the ionizers.

Main Results:

  • Both tested air ionizer systems demonstrated significant efficacy in reducing airborne MS2 virus concentrations.
  • One system achieved an 82.02% reduction, while the other achieved an 81.72% reduction in airborne MS2.
  • These results indicate a substantial inactivation of the surrogate virus by the tested air ionizers.

Conclusions:

  • Commercial air ionizers show promise as effective tools for inactivating airborne microorganisms, including viral surrogates.
  • Air ionizer technology can contribute to mitigating the spread of airborne infectious diseases.
  • Further research is recommended to validate efficacy against specific airborne viruses like influenza and SARS-CoV-2 strains.

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