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Updated: May 20, 2025
In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
Published on: December 9, 2015
Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy
Syeda Azam Najam1, Xain Tauqeer2, Aamna Hassan1
1Department of Nuclear Medicine, Shaukat Khanum Memorial Trust, Lahore, Pakistan.
Abstract:
Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvement and variable visceral manifestations. Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosis and disease mapping. ECD's course depends on extraosseous involvement, with potential complications including heart and renal failure. We present the case of ECD with bilateral leg pain and orbital involvement. Imaging revealed mixed sclerotic and lytic skeletal lesions, cerebellar lesions, intraorbital soft tissue masses, mediastinal and retroperitoneal infiltration.
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