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Updated: May 20, 2025

Ratiometric Imaging of Extracellular pH in Dental Biofilms
Published on: March 9, 2016
Ion release dynamics of bioactive resin cement under variable pH conditions
Venkata Suresh Venkataiah1, Jogikalmat Krithikadatta1, Kavalipurapu Venkata Teja2
1Department of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Bioactive resin cements release more ions in acidic conditions, with recharging enhancing this effect. This pH-dependent ion release is crucial for dental restoration longevity and remineralization.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
Background:
- Bioactive resin cements are vital in restorative dentistry for their ion-releasing properties.
- Sustained ion release, particularly under cariogenic pH, promotes remineralization and extends restoration lifespan.
Purpose of the Study:
- To investigate the impact of pH on ion release from bioactive resin cements.
- To assess the effect of recharging on ion release profiles.
Main Methods:
- Specimens of bioactive resin cement were exposed to pH 4.5, 5.5, and 6.5.
- Calcium, fluoride, and phosphate ion release were quantified before and after recharging with casein phosphopeptide-amorphous calcium phosphate with fluoride (CPP-ACPF).
Main Results:
- Higher calcium, fluoride, and phosphate release occurred at acidic pH (4.5-5.5) before and after recharging.
- Recharging sustained ion availability, with no initial burst release observed.
Conclusions:
- Bioactive resin cement ion release is pH-dependent.
- Regular recharging is essential for maintaining therapeutic ion release.
- The unique release kinetics may benefit long-term remineralization in dental restorations.
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