Is timing everything? Examining operative time in lung transplants from 2006 to 2023
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View abstract on PubMed
Summary
This summary is machine-generated.Lung transplant surgery timing does not impact long-term survival. While nighttime transplants showed minor increases in complications, overall patient outcomes remained unaffected by operative time.
Area Of Science
- Thoracic Surgery
- Transplantation Medicine
- Health Services Research
Background
- Conflicting evidence exists regarding the impact of lung transplant surgery timing on patient outcomes.
- Previous studies have not definitively established a link between operative times and recipient success.
Purpose Of The Study
- To evaluate the association between the time of lung transplant surgery and recipient outcomes.
- To determine if specific operative times influence post-transplant survival and complications.
Main Methods
- Analysis of adult primary lung transplants from the United Network for Organ Sharing Database.
- Stratification of patients into four operative time groups (T1-T4).
- Comparative statistics, Kaplan-Meier survival analysis, and multivariate Cox proportional hazard modeling were employed.
Main Results
- The T4 (6 PM-12 AM) group showed a minor increase in length of stay and primary graft dysfunction.
- No significant difference in long-term survival was observed among the four operative time groups (p=0.55).
- Operative time was not independently associated with decreased long-term mortality; recipient factors like diabetes and creatinine were significant predictors.
Conclusions
- Peri-operative complications during nighttime lung transplants (T4) did not affect long-term survival.
- Thoracic transplantation can be safely performed at any time.
- Surgical teams may benefit from performing transplants during standard work hours for improved provider well-being.
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