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Related Experiment Video

Updated: Apr 28, 2026

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Deep enteroscopy in children: techniques, applications, and future directions.

Brett J Hoskins1

  • 1Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at IU Health, Indianapolis, IN, United States.

Frontiers in Pediatrics
|March 27, 2025
PubMed
Summary

Deep enteroscopy techniques, including push enteroscopy (PE) and balloon-assisted enteroscopy (BAE), significantly improve diagnosis and treatment for pediatric small bowel disorders. BAE offers deeper access for complex conditions, enhancing patient outcomes.

Keywords:
balloon-assisted enteroscopydiagnostics and therapeuticsdouble-balloon enteroscopypediatric deep enteroscopypediatric gastroenterologypush enteroscopysingle-balloon enteroscopysmall bowel disorders

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Area of Science:

  • Pediatric Gastroenterology
  • Minimally Invasive Endoscopy
  • Gastrointestinal Diagnostics

Background:

  • Deep enteroscopy, comprising push enteroscopy (PE) and balloon-assisted enteroscopy (BAE), has transformed pediatric small bowel disorder management.
  • PE is useful for proximal small bowel issues, but BAE techniques (single-balloon enteroscopy [SBE] and double-balloon enteroscopy [DBE]) offer superior depth and stability for comprehensive evaluation and treatment.

Purpose of the Study:

  • To review the evolving role and effectiveness of deep enteroscopy techniques in diagnosing and treating pediatric small bowel disorders.
  • To highlight the diagnostic yields, therapeutic capabilities, safety profiles, and challenges associated with PE and BAE in children.
  • To identify future directions, including comparative analyses and technological advancements, for optimizing deep enteroscopy in pediatric care.

Main Methods:

  • Review of current literature on deep enteroscopy (PE, SBE, DBE) in pediatric patients.
  • Analysis of diagnostic yields and therapeutic interventions for various small bowel conditions (e.g., obscure GI bleeding, Crohn's disease, tumors).
  • Evaluation of safety data and complication rates in pediatric populations.

Main Results:

  • BAE techniques provide deeper access and enable advanced interventions like polypectomy, stricture dilation, and hemostasis in the pediatric small bowel.
  • Pediatric data show high diagnostic yields for BAE, with comparable outcomes between SBE and DBE.
  • While generally safe, younger children may have slightly higher complication rates due to anatomical factors.

Conclusions:

  • Deep enteroscopy, particularly BAE, is a valuable tool for managing pediatric small bowel disorders, offering high diagnostic and therapeutic success.
  • Further research, standardized training, and comparative studies with capsule endoscopy are needed to refine procedural selection and optimize outcomes.
  • Technological innovations and tailored pediatric approaches will further enhance the role of deep enteroscopy in children's gastrointestinal health.