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Updated: May 20, 2025

A Rat Model of EcoHIV Brain Infection
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Actinomyces israelii Brain Abscess With Advanced HIV Disease.

Laura Leite-Almeida1,2, Maria Sousa3, Teresa Magalhães4

  • 1Pediatrics, Unidade Local de Saúde de São João, Porto, PRT.

Cureus
|March 27, 2025
PubMed
Summary

This case report details a pediatric central nervous system (CNS) abscess caused by Actinomyces israelii in a child with advanced HIV. Early diagnosis and multidisciplinary treatment led to a full recovery without relapse.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

Keywords:
actinomyces israeliibacterial cns infectionbrain abscesscombination antiretroviral therapypediatric hiv infection

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  • Actinomyces israelii is a rare cause of central nervous system (CNS) infections, particularly in pediatric populations.
  • Advanced Human Immunodeficiency Virus (HIV) disease can predispose individuals to opportunistic infections, including CNS abscesses.
  • Pediatric CNS lesions in immunocompromised patients require a broad differential diagnosis.