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[Invasive pneumococcal disease in Norway 2004–23 and choice of vaccine for older adults].

Jacob Dag Berild1, Anja Bråthen Kristoffersen2, Brita Askeland Winje3

  • 1Avdeling for smittevern og vaksine, Folkehelseinstituttet.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|March 27, 2025
PubMed
Summary
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Invasive pneumococcal disease (IPD) incidence significantly decreased in children and older adults after vaccine introduction. Continued vaccination is crucial for preventing residual IPD cases in the elderly, targeting prevalent serotypes.

Area of Science:

  • Epidemiology
  • Vaccinology
  • Public Health

Context:

  • Invasive pneumococcal disease (IPD) prevention relies on serotype-specific vaccines.
  • Vaccine effectiveness is influenced by vaccine serotype composition and circulating strains.
  • The introduction of the pneumococcal vaccine into Norway's Childhood Immunisation Programme in 2006 marked a significant public health intervention.

Purpose:

  • To analyze the epidemiological shifts in IPD following the 2006 vaccine program implementation in Norway.
  • To assess the impact of childhood vaccination on IPD epidemiology across different age groups.
  • To inform vaccine selection strategies for older adults based on current IPD trends.

Summary:

  • A total of 13,767 IPD cases were reported between 2004-2023.

Related Experiment Videos

  • IPD incidence in children under 5 dropped by 70%, and in adults 65 and older by 55%.
  • Post-2014, common serotypes in older adults included 22F, 3, 8, 9N, and 23B.

    • Impact:

    • Childhood vaccination has indirectly reduced IPD burden in older populations.
    • A substantial burden of IPD persists in older adults, highlighting the need for targeted vaccination.
    • Current vaccines (23-valent polysaccharide, 20- and 21-valent conjugate) offer broad coverage for prevalent IPD serotypes in the elderly.