Fatal Case of Splash Pad-Associated Naegleria fowleri Meningoencephalitis - Pulaski County, Arkansas, September 2023

Insights

A fatal case of primary amebic meningoencephalitis (PAM) in Arkansas was linked to a splash pad with inadequate disinfection. This highlights the risk of Naegleria fowleri in recreational water venues.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Environmental Health

Background:

  • Primary amebic meningoencephalitis (PAM) is a rare but often fatal brain infection caused by Naegleria fowleri.
  • Recreational water venues, including splash pads, can pose an exposure risk if water is not adequately disinfected.

Purpose of the Study:

  • To report a fatal case of PAM in Arkansas linked to a splash pad.
  • To emphasize the importance of proper disinfection and management of recreational water facilities to prevent Naegleria fowleri infections.

Main Methods:

  • Epidemiologic, laboratory, and environmental data collection and analysis.
  • Public health investigation following a confirmed case of PAM.

Main Results:

  • A fatal case of PAM was diagnosed in a child in Arkansas in September 2023.
  • Investigation identified a splash pad with inadequately disinfected water as the likely source of Naegleria fowleri exposure.
  • This is the third reported splash pad-associated PAM case in the U.S., all linked to insufficient disinfection.

Conclusions:

  • Splash pads with inadequately disinfected water are a potential source of Naegleria fowleri exposure.
  • PAM should be considered in patients with acute meningoencephalitis and a history of freshwater exposure, including recreational water.
  • Proper design, operation, and management of splash pads are crucial for preventing Naegleria fowleri infections and other illnesses.

Related Concept Videos

Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...