Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adult ALCAPA Presenting with Apical Left Ventricular Aneurysm and Ventricular Arrhythmia.

Journal of cardiovascular echography·2026
Same author

An in situ non-contact 3D microscopic measurement system for temporal bone anatomy based on stereo imaging.

Scientific reports·2026
Same author

In Vivo Evidence of Human Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 Mediated Disposition of Glycyrrhizin and Its Drug-Drug Interactions in Humanized Mice.

Phytotherapy research : PTR·2026
Same author

Data-Driven, Mechanistically Guided Prediction of Yield and Chemoselectivity in SuFEx Reactions.

Journal of the American Chemical Society·2026
Same author

Clinical characteristics of hospitalized patients with benign gallbladder disease: a large-scale retrospective analysis.

BMC gastroenterology·2026
Same author

A horizontal connectivity mode in coastal oceans: transport overrides stratification to govern microbiome network stability.

Applied and environmental microbiology·2026

Related Experiment Video

Updated: May 10, 2026

Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

Nomogram for predicting olfactory disorder in obstructive sleep apnea: A retrospective study based on a multicenter

Jiajia Dong1, Xiao Yu2, Yazhu Liang3

  • 1Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Plos One
|March 27, 2025
PubMed
Summary

Obstructive sleep apnea (OSA) increases olfactory disorder (OD) risk. A new nomogram using age, sex, and oxygen levels aids early OD detection in OSA patients, improving personalized care.

More Related Videos

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

Related Experiment Videos

Last Updated: May 10, 2026

Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

Area of Science:

  • Sleep Medicine
  • Otolaryngology
  • Diagnostic Tools

Background:

  • Obstructive sleep apnea (OSA) is linked to an increased risk of olfactory disorder (OD).
  • Olfactory disorder may signal adverse health outcomes in OSA patients.
  • Early detection of OD in OSA is crucial for timely intervention.

Purpose of the Study:

  • To develop and validate a predictive nomogram for early detection of olfactory disorder (OD) in patients with obstructive sleep apnea (OSA).
  • To provide a clinical tool for identifying OSA patients at high risk for OD.

Main Methods:

  • Retrospective analysis of 125 OSA patients for nomogram development and internal validation.
  • External validation using data from 30 OSA patients.
  • Utilized polysomnography (PSG) and Sniffin' Sticks test results.

Main Results:

  • The developed nomogram incorporates age, sex, and time with oxygen saturation below 90%.
  • Achieved an area under the receiver operating characteristic curve of 0.814 (internal validation) and 0.778 (external validation).
  • Demonstrated excellent discrimination and calibration, indicating clinical utility.

Conclusions:

  • A nomogram based on clinical and PSG data can effectively detect OD in OSA patients.
  • This tool facilitates patient stratification and personalized treatment strategies.
  • Aids clinicians in managing olfactory dysfunction in the context of OSA.