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Published on: November 1, 2024
Isotretinoin use in rhinoplasty patients
Jholbert Cardoso Santana1, Hugo Valter Ramos Lisboa1, Leandro Azevedo de Camargo1
1Hospital das Clínicas da Universidade Federal de Goiás (HC-UFG), Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Goiânia, GO, Brazil.
Objective:
Presenting evidence available on perioperative isotretinoin application in, and benefits for, thick-skinned patients subjected to rhinoplasty.
Methods:
Analysis was applied to articles available in the following databases: Cochrane, PubMed, ScienceDirect and Scielo. The analyzed corpus comprised studies published from 2004 to 2023 focused on investigating thick-skinned patients subjected to rhinoplasty and treated with isotretinoin. Inappropriate and unrelated methodologies were excluded from the analysis.
Results:
Initially, 1,214 articles were collected, but this number dropped to 617 after duplicates' removal. Twenty (20) articles remained in the corpus after inclusion criteria application, but 10 of them were excluded from the analysis based on exclusion criteria. Finally, 10 articles were selected for review purposes: 1 experience report, 2 case studies, 3 narrative reviews and 4 clinical trials.
Conclusions:
The current findings suggested aesthetic improvements in patients treated with isotretinoin, although its long-term benefits remain uncertain. Thus, further research on this topic should be conducted.
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