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The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS): Normative values with gender, age and
Melike Batum1, Ayşegül Şeyma Sarıtaş1, Bahadır Erdoğan1
1Celal Bayar University Neurology Department Manisa, Türkiye.
Abstract:
Cognitive impairment is common in multiple sclerosis (MS) and can be demonstrated in all stages and subtypes of the disease. The most recently created battery to evaluate information processing speed, verbal and visual memory to evaluate cognitive functions in MS is the Brief International Cognitive Assessment for MS (BICAMS). The aim of this study is to predict the normal values of BICAMS for our society according to age, gender, and education duration. Two hundred ninety-four healthy volunteers, grouped by age, gender, and education duration, were included in the study. Symbol Digit Modalities Test (SDMT), California Verbal Learning Test II (CVLT-II), and Brief Visuospatial Memory Test-Revised (BVMTR) tests included in the BICAMS battery were applied to all patients. Linear regression analysis method was used to estimate the expected BICAMS test scores of the study participants according to their age, gender and education period. There was no difference between SDMT, CVLT-II, and BVMT-R results in men and women (p = 0.354, p = 0.110, p = 0.410, respectively). SDMT, CVLT-II, and BVMT-R results differed significantly in all age and education level groups (p < 0.001). It was determined that the most effective factor that effects the BICAMS results was the education level. It is thought that normal values for age, gender, and education level can facilitate the use of the battery in clinical practice, as well as for longitudinal patient assessments.
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