Related Experiment Video

Updated: Jun 19, 2026

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells
11:35

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Published on: June 16, 2017

Engineered circular guide RNAs enhance miniature CRISPR/Cas12f-based gene activation and adenine base editing

Xin Zhang1,2, Mengrao Li1, Kechen Chen1

  • 1Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, Southern Medical University, Guangzhou, China.

Nature Communications
|March 28, 2025
PubMed

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