Enteral feeding in pediatric patients with bronchiolitis requiring non-invasive support via nasal interface

Kelsey Finnegan1, Julia Smalley1, Barbara Gallagher1

  • 1Division of Pediatric Critical Care Medicine, MassGeneral Brigham for Children, Boston, MA, USA.

Pediatric Research
|March 28, 2025
PubMed

Insights

Oral feeding in children with bronchiolitis on non-invasive respiratory support is safe and reduces pneumonia risk and hospital stay. Nasogastric feeding increased pneumonia odds.

Area of Science:

  • Pediatric critical care medicine
  • Pediatric pulmonology
  • Neonatal and infant nutrition

Background:

  • Enteral feeding is crucial for critically ill children.
  • Non-invasive respiratory support may delay feeding due to safety concerns.
  • Bronchiolitis is a common respiratory illness in infants.

Purpose of the Study:

  • To investigate the safety of oral versus nasogastric feeding in children with bronchiolitis on non-invasive respiratory support.
  • To determine the association between feeding method and adverse events, including pneumonia and respiratory support escalation.
  • To evaluate the impact of feeding method on length of stay.

Main Methods:

  • Retrospective cohort study of 407 patients aged 0-24 months with bronchiolitis.
  • Patients received non-invasive respiratory support via nasal interfaces.
  • Comparative statistics and multivariable regression analyzed feeding method (oral vs. nasogastric) and clinical outcomes.

Main Results:

  • Nasogastric feeding was associated with a 4.65-fold increased odds of developing new pneumonia compared to oral feeding.
  • No significant differences in pneumonia development, respiratory support escalation, or highest support level were found based on feeding method.
  • Oral feeding was linked to decreased pediatric intensive care unit and overall hospital lengths of stay.

Conclusions:

  • Enteral feeding via mouth or orogastric tube is safe for children with bronchiolitis on non-invasive respiratory support.
  • Oral feeding is associated with a reduced risk of pneumonia and shorter hospital stays.
  • Further research is needed to assess long-term safety and nutritional adequacy of oral feeding in this population.
Abstract

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