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Updated: Jul 20, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Suppressive Antibiotic Therapy in Prosthetic Joint Infections: A Contemporary Overview
Hajer Harrabi1, Eloïse Meyer1, Nathalie Dournon1
1Infectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Abstract:
The management of prosthetic joint infections (PJIs) poses significant challenges, requiring a multidisciplinary approach involving surgical, microbiological, and pharmacological expertise. Suppressive antibiotic therapy (SAT) has emerged as a viable option in cases where curative interventions are deemed unfeasible. This review provides an updated synthesis of recent evidence on SAT, including its indications, efficacy, practical considerations, and associated challenges. We aim to highlight the nuances of this therapeutic approach, discuss the factors influencing its success, and offer future directions for research to optimize patient outcomes.
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