Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

1.3K
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
1.3K
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

1.5K
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
1.5K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

440
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
440
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

702
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
702
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

869
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
869
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

1.0K
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Innervated Muscle Transfer for Dynamic Abdominal Wall Reconstruction: Principles, Techniques, and Outcomes.

Seminars in plastic surgery·2026
Same author

Innovations in Reconstructive Microsurgery: A Series of Challenging Cases and Novel Techniques.

Seminars in plastic surgery·2026
Same author

Chang Gung Experience (Part 4): Organization of a Microsurgical Center for Service Education and Research and Miscellaneous Microsurgical Reconstruction.

Seminars in plastic surgery·2026
Same author

Neuroplastic and Augmented Reality Integration in Moyamoya Revascularization: A Reconstructive Microsurgical Paradigm.

Seminars in plastic surgery·2026
Same author

Natural Products in Clear Cell Renal Cell Carcinoma: Rewiring the VHL-HIF Axis, Metabolic Plasticity, and Tumor-Immune Interactions.

International journal of molecular sciences·2026
Same author

Impact of Fixation Methods on Long-Term Bone Graft Hypertrophy in Free Fibular Flap Transfer: Analysis of 51 Lower-Limb Reconstructions.

Plastic and reconstructive surgery·2026

Related Experiment Video

Updated: May 7, 2026

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer
09:24

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

8.4K

Improving Risk Stratification in pT3 Upper Tract Urothelial Carcinoma: A Focus on Invasion Patterns.

Yung-Tai Chen1,2, Hsiang-Ying Lee3,4,5, Wen-Jeng Wu3,4,5

  • 1Department of Urology, Taiwan Adventist Hospital, Taipei 10556, Taiwan.

Cancers
|March 28, 2025
PubMed
Summary
This summary is machine-generated.

A new subclassification for upper tract urothelial cancer (UTUC) pT3 tumors is proposed. It incorporates fat and parenchyma invasion, improving risk stratification for better patient outcomes in UTUC treatment.

Keywords:
nephroureterectomypathological stageupper urinary tract urothelial cancer

More Related Videos

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

9.5K
Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
06:39

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Published on: November 22, 2019

7.1K

Related Experiment Videos

Last Updated: May 7, 2026

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer
09:24

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

8.4K
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

9.5K
Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
06:39

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Published on: November 22, 2019

7.1K

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Existing T3 subclassifications for upper tract urothelial cancer (UTUC) lack specificity and focus primarily on renal pelvis tumors.
  • This heterogeneity limits accurate risk stratification and treatment guidance for pT3 UTUC patients.

Purpose of the Study:

  • To develop and propose a novel pT3 subclassification system tailored for upper tract urothelial cancer (UTUC).
  • To address the limitations of current subclassifications by incorporating specific pathological features relevant to all UTUC sites.

Main Methods:

  • Analysis of 120 pT3 UTUC cases from a Taiwanese multicenter registry.
  • Standardized pathology reporting and evaluation by a single pathologist to ensure consistency.

Main Results:

  • Univariate analysis indicated survival variations among existing subclassifications.
  • Multivariate analysis identified concurrent fat and parenchyma invasion as an independent predictor of poorer overall survival (OS), cancer-specific survival (CSS), and disease-free survival (DFS).

Conclusions:

  • A novel pT3 subclassification for UTUC is proposed, integrating fat and parenchyma invasion.
  • This system is applicable across all UTUC locations and may enhance risk stratification and patient outcomes.